मात्राया नास्त्यवस्थानं दोषमग्निं बलं वयम्
व्याधिं द्रव्यम् च कोष्ठश्च वीक्ष्यमात्रं प्रयोजयेत
xxxx In Ayurveda the dose to be administered depends on so many factors.Those factors include dosha,the digestive power of the patient,strength of the patient,his age,the disease and the ingredients of the yoga(medicine to be prescribed).
xxxx It was Sharangdhara in his book 'Sharandhara Samhitha', who described the dose calculation along with all the necessary factors for determining doses.
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